Tandutinib intermediate CAS 288383-71-1
Identification
CAS Number
288383-71-1
Name
4-chloro-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazoline
Synonyms
Tandutinib intermediate
MLN518
CT53518
Molecular Structure
SMILES
Clc3ncnc2cc(OCCCN1CCCCC1)c(OC)cc23
StdInChI
InChI=1S/C17H22ClN3O2/c1-22-15-10-13-14(19-12-20-17(13)18)11-16(15)23-9-5-8-21-6-3-2-4-7-21/h10-12H,2-9H2,1H3
StdInChIKey
QMPMEXBHMIYNGL-UHFFFAOYSA-N
Molecular Formula
C17H22ClN3O2
Molecular Weight
335.83
Properties
Appearance
White or almost white crystalline powder
Refractive Index
n20/D1.583(lit.)
Boiling Point
485.69 °C at 760 mmHg
Flash Point
247.537 °C
Density
1.215 g/ml
Safety Data
Symbol
GHS07
Signal Word
Warning
Hazard Statements
Precautionary Statements
Personal Protective Equipment
dust mask type(N95) US, Eye Shields, Gloves
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
26-36
Specifications and Other Information of Our Tandutinib intermediate CAS 288383-71-1
Purity
98%min(By HPLC)
Identification
HNMR, HPLC
Known Application
It is an intermediate(CAS 288383-71-1) of the Tandutinib, which is an orally active multitargeted tyrosine kinase inhibitor that is currently under evaluation for the treatment of glioblastoma and has been used in the treatment of leukemia.
Productivity
kg scale
Watson-Int Link
http://watson-int.com/Intermediate-of-tandutinib_CAS_288383-71-1.html