Sulfamethoxazole EP Impurity A2 CAS 723-46-6

Sulfamethoxazole EP Impurity A2 CAS 723-46-6

Identification

CAS Number

723-46-6

Name

ulfamethoxazole EP Impurity A2

SMILES

Cc1cc(no1)NS(=O)(=O)c2ccc(cc2)N

StdInChI

InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

StdInChIKey

JLKIGFTWXXRPMT-UHFFFAOYSA-N

Molecular Formula

C10H11N3O3S

Molecular Weight

253.278

EINECS

211-963-3

MDL Number

MFCD00010546

Properties

Appearance

A white or almost white, crystalline powder.

Melting Point

169°C to 172°C

Infrared absorption spectrophotometry

The Infrared absorption Spectrum of sample is concordant with the spectrum of Sulfamethoxazole CRS.

Safety Data

Symbol

exclamation-mark-jpgexclamation-mark-jpgGHS07, GHS08

Signal Word

Warning

Hazard statements

H315-H319-H335

Precautionary Statements

P305 + P351 + P338

WGK Germany

3

Specifications and Other Information of Our

Identification Methods

HNMR, HPLC

Purity

99% min

Loss on Drying

NMT 0.5% w/w

Impurity A (Acetyl SMZ)

NMT 0.1 %

Impurity B (Sulfanilyl SMZ)

NMT 0.1 %

Impurity C (Isoxamine)

NMT 0.1 %

Impurity D (Sulfanilic acid)

NMT 0.1 %

Impurity E (Sulfanilamide)

NMT 0.1 %

Impurity F Isomeric (SMZ)

NMT 0.1 %

Any other Impurity

NMT 0.1 %

Total Impurities

NMT 0.3%

Shelf Life

5 years

Storage

Under room temperature away from light

Known Application

Sulfamethoxazole EP are mainly used to treat acute and chronic urinary tract infections, and can also be used to prevent meningitis and acute otitis media caused by influenza bacilli.

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