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(S)-N-(2′,6′-dimethylphenyl)-piperidine-2- carboxylic amide CAS 27262-40-4

(S)-N-(2′,6′-dimethylphenyl)-piperidine-2- carboxylic amide CAS 27262-40-4

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    • Identification

    CAS Number

    27262-40-4

    Name

    (S)-N-(2′,6′-dimethylphenyl)-piperidine-2- carboxylic amide

    Synonyms

    (+)-2′,6′-pipecoloxylidide
    (2S)-N-(2,6-Dimethylphenyl)-2-piperidincarboxamid [German] [ACD/IUPAC Name]
    (2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide [ACD/IUPAC Name]
    (2S)-N-(2,6-Diméthylphényl)-2-pipéridinecarboxamide [French] [ACD/IUPAC Name]
    (2S)-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
    (S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide
    27262-40-4 [RN]
    2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-, (2S)- [ACD/Index Name]
    (2S)-N-(2,6-Dimethylphenyl)-2-piperidinecarboxamide)
    (2S)-N-(2,6-dimethylphenyl)pipecolinamide
    (s)- n-(2,6-dimethylphenl)-2-piperidine carboxamide
    (S)-2′,6′-Pipecoloxylidide
    (S)-N-(2 inverted exclamation marka,6 inverted exclamation marka-dimethylphenl)-2-Piperidine Carboxamide
    (s)-n-(2,6-dimethylphenl)-2-piperidine carboxamide
    (S)-N-(2′,6′-dimethylphenl)-2-Piperidine carboxamide
    (S)-N-(2′,6′-Dimethylphenl)-2-piperidinecarboxamide
    (S)-N-(2′,6′-Dimethylphenyl)-2-Piperidinecarboxamide (en)
    (S)-N-(2,6-dimethylphenyl)-piperidine-2- carboxylic amide
    (S)-N-(2′,6′-dimethylphenyl)-piperidine-2- carboxylic amide
    (s)-n-(2,6-dimethylphenyl)-piperidine-2- carboxylic??amide
    (S)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
    (S)-N-(2′,6′-Dimethylphenyl)piperidine-2-carboxylic amide
    (S)-N-(2′,6′-DIMETHYLPHENYL)-PIPERIDINE-2-CARBOXYLIC AMIDE
    (S)-N-(2??,6??-dimethylphenl)-2-Piperidine Carboxamide
    (S)-piperidine-2-carboxylic acid 2,6-dimethylphenyl amide
    [27262-40-4] [RN]
    1272756-18-9 [RN]
    15883-20-2 [RN]
    2,2-Dimethylpropionic acid hydrazide
    2′,6′-Pipecoloxylidide
    2′,6′-PIPECOLOXYLIDIDE, (+)-
    BR-27260
    Demethylmepivacaine, (+)-
    Desbutylbupivacaine, (+)-
    FS-2874
    MFCD09038786 [MDL number]
    n-despropyl ropivacaine
    QA-3162
    UNII-NF8RN1V7VM

    SMILES

    Cc1cccc(c1NC(=O)[C@@H]2CCCCN2)C

    StdInChI

    InChI=1S/C14H20N2O/c1-10-6-5-7-11(2)13(10)16-14(17)12-8-3-4-9-15-12/h5-7,12,15H,3-4,8-9H2,1-2H3,(H,16,17)/t12-/m0/s1

    StdInChIKey

    SILRCGDPZGQJOQ-LBPRGKRZSA-N

    Molecular Formula

    C14H20N2O

    Molecular Weight

    232.321 

    MDL Number

    MFCD09038786

    Properties

    Appearance

    White to almost white crystalline powder

    Melting Point

    127°C~131°C

    Safety Data

    RIDADR 

    NONH for all modes of transport

    WGK Germany

    3

    Specifications and Other Information of Our (S)-N-(2′,6′-dimethylphenyl)-piperidine-2- carboxylic amide CAS 27262-40-4

    Identification Methods

    IR Spectrum Sample should be consistent with the reference spectrum

    Purity

    98% min

    Optical Purity

    ≥98%

    Optical Isomer

    ≤0.5%

    Specific Optical Rotation

    +44.0°~ +52.0°

    Metallic Residue

    Pd: ≤1ppm

    Loss on Drying

    ≤0.5%

    Related Substances

    Picolinic acid

    ≤0.10%

    2,6-dimethylanilinc

    ≤0.10%

    L-dibenzoyl tartaric acid

    ≤0.10%

    N-(2 ‘,6’ -Dimethylphenyl)-2-Picolinamide

    ≤0.10%

    Unknown impurity

    ≤0.10%

    Total Impurities

    ≤1.0%

    Residual Solvents

    Ethanol

    ≤5000ppm

    Benzene

    ≤2ppm

    Toluene

    ≤890ppm

    Acetic acid

    ≤5000ppm

    Shelf Life

    2 years

    Storage

    Under room temperature away from light

    Productivity

    2MT/month

    Known Application

    Used as an intermediate of ropivacaine hydrochloride, it is also commonly used in the development of antidepressants, analgesics and other central nervous system drugs.

    This product is developed by our R&D company Watson International Ltd (https://www.watson-int.com/).