Mirtazapine CAS 61337-67-5 (85650-52-8)

Identification

CAS Number

61337-67-5 or 85650-52-8

Name

Mirtazapine

Synonyms

2-Methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine
2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepin
2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepin
2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
2-méthyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazépine
2-Méthyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazépine
Avanza
mirtazapina
mirtazapinum
Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-
Remeron
Zispin
(14bR)-2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
(rs)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino-(2,1-a)pyrido(2,3-c)(2)benzazepine
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c](2)benzazepine
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
2-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene
5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8(13),9,11,16,18-hexaene
5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8(13),9,11,15,17-hexaene
6-AZAMIANSERIN
Azamianserin
Mepirzapin
mepirzepine
Mirtazanine
Mirtazepine
Mirtazipine
Norset
Promyrtil
Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-
Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, (±)-
Remergil
Remergon
Remeron
Rexer

Molecular Structure

structure of Mirtazapine CAS 61337-67-5 (85650-52-8)

SMILES

CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4

StdInChI

InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3

StdInChIKey

RONZAEMNMFQXRA-UHFFFAOYSA-N

Molecular Formula

C17H19N3

Molecular Weight

265.35

MDL Number

MFCD00865427

EINECS

288-060-6

Properties

Appearance

A white or almost white crystalline powder

Solubility

Freely soluble in methanol and in toluene, soluble in ethylether, sparingly soluble in hexane, practically insoluble in water.

Safety Data

Personal Protective Equipment

Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

WGK Germany

3

Specifications and Other Information of Our Mirtazapine CAS 61337-67-5 (85650-52-8)

Standard

USP

Identification

IR

Assay

98%-102% (anhydrate substance)

Water

1.0%-3.5%

Residue on Ignition

0.1% max

Heavy Metals

10ppm max

Residual Solvents

Dimethyl sulfoxide: 880ppm max
Tetrahydrofuran: 720ppm max
Toluene: 890ppm max
Chloroform: 60ppm max
N-heptane: 500ppm max
Ethanol: 5000ppm max

Impurities

Impurity A: 0.10% max
Impurity B: 0.10% max
Impurity C: 0.10% max
Impurity D: 0.10% max
Impurity E: 0.10% max
Individual unspecified impurity: 0.10% max
Total impurities: 0.50% max

Package

25kg/drum

Manufacturing Capacity

1 MT/year

Storage

Under room temperature,away from light

Application

Mirtazapine (brand names: Avanza (AU, NZ), Axit (AU), Mirtaz (IN, IE†), Mirtazon (AU), Remeron (AU, CA, HK, IL, NZ†, RU, SG, ZA, US), Zispin (IE, UK); where † indicates discontinued products) is a noradrenergic and specific serotonergic antidepressant (NaSSA) that was introduced by Organon International in the United States in 1996 and is used primarily in the treatment of depression. It is also commonly used as an anxiolytic, hypnotic, antiemetic and appetite stimulant. In terms of structure, mirtazapine can also be classified as a tetracyclic antidepressant (TeCA).

Watson-Int Link

http://watson-int.com/Mirtazapine_CAS_61337-67-5_85650-52-8.html