Lercanidipine HCL CAS 132866-11-6
Identification
CAS Number
132866-11-6
Name
Lercanidipine HCL
Synonyms
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride
Zanidip
Lerdip
Molecular Structure
SMILES
Cl.[O-][N+](=O)c1cccc(c1)C4C(=C(/NC(=C4C(=O)OC(C)(C)CN(CCC(c2ccccc2)c3ccccc3)C)C)C)C(=O)OC
StdInChI
InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H
StdInChIKey
WMFYOYKPJLRMJI-UHFFFAOYSA-N
Molecular Formula
C36H41N3O6.HCL
Molecular Weight
648.19
Properties
Appearance
Light yellow to yellow powder
Melting Point
185-190°C
Boiling Point
712.5 °C at 760 mmHg
Flash Point
384.7 °C
Safety Data
Symbol
GHS06
Signal Word
Danger
Hazard Statements
Precautionary Statements
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
36/37-45
RIDADR
UN 2811 6.1/PG 3
WGK Germany
3
Specifications and Other Information of Our Lercanidipine HCL CAS 132866-11-6
Purity
99.5% min
Single Impurity
0.07% max
Loss on Drying
0.5% max
Heavy Metals
20 ppm max
Known Actions
It is a L-type vascular channel antagonist; L-type cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.
Known Application
It is also called Lercanidipine or Zanidip, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. This lowers the blood pressure and allows the heart to work more efficiently.
Productivity
500kg/month
Storage
2-8°C away from light, keep dry.