Glycopyrrolate CAS 596-51-0

Identification

CAS Number

596-51-0

Name

Glycopyrrolate

Synonyms

α-cyclopentylmandelic acid ester with 3-hydroxy-1,1-dimethylpyrrolidinium bromide
1-methyl-3-pyrrolidyl α-cyclopentylmandelate methobromide
1-methyl-3-pyrrolidyl α-phenyl-α-cyclopentylglycolate methobromide
3-(2-phenyl-2-cyclopentylglycoloyloxy)-1,1-dimethylpyrrolidinium bromide
3-hydroxy-1,1-dimethylpyrrolidinium bromide α-cyclopentylmandelate
AHR-504
Copyrrolate
Gastrodyn
NSC 250836
NSC 251251
NSC 251252
NVA-237
glycopyrronium bromide

Molecular Structure

Structure of Glycopyrrolate CAS 596-51-0

SMILES

O=C(OC1CC[N+](C)(C)C1)C(O)(c2ccccc2)C3CCCC3

StdInChI

InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1

StdInChIKey

ANGKOCUUWGHLCE-UHFFFAOYSA-N

EINECS

209-887-0

Molecular Formula

C19H28NO3.Br

Molecular Weight

398.34

MDL Number

MFCD00072137

Properties

Appearance

Off-white to white crystalline powder

Solubility

H2O: ≥24 mg/mL

Melting Point

193-198 °C

Safety Data

Symbol

exclamation-mark-jpgGHS07

Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Hazard Codes (Europe)

Xi

Risk Statements (Europe)

36/37/38

Safety Statements (Europe)

26

WGK Germany

3

Specifications and Other Information of Our Glycopyrrolate CAS 596-51-0

Standard

USP

Assay

98.0%-100.5%

Ordinary Impurities

Single: 0.5% max
Total: 2.0% max

Related Compounds

Single: 0.1% max
Total: 0.5% max

Residual Solvents

Methyl Alcohol: 3000ppm max
Isopropyl ether: 5000ppm max
2-Butanone: 3000ppm max
n-Heptane: 5000ppm max
Particle Size: D90:≤80µm

Other Doccuments Avaiable

DMF

Identification Method

IR, HPLC

Known Application

In anesthesia, glycopyrrolate injection can be used as a preoperative medication in order to reduce salivary,tracheobronchial, and pharyngeal secretions, as well as decreasing the acidity of gastric secretion. It is also used in conjunction with neostigmine, a neuromuscular blocking reversal agent, to prevent neostigmine’s muscarinic effects such as bradycardia. It is also used to reduce excessive saliva (sialorrhea). It decreases acid secretion in the stomach and so may be used for treating stomach ulcers, in combination with other medications. Use in treating asthma and COPD has been described. It has been used topically and orally to treat hyperhidrosis.

Productivity

kg scale

Storage

2-8°C

General View of Documents

Glycopyrrolate CAS 596-51-0 HPLC

Glycopyrrolate CAS 596-51-0 HPLC

Watson-Int Link

http://watson-int.com/Glycopyrrolate_CAS_596-51-0.html