BP-1-102 CAS 1334493-07-0

Name

BP-1-102

Synonyms

Molecular Formula

C29H27F5N2O6S

Molecular Weight

626.601

CAS Number (Or Watson Number for Non-CAS Products)

1334493-07-0

EINECS

Specs/Standards

98%min

Use

BP-1-102 is a potent, orally bioavailable and selective STAT3 inhibitor. BP-1-102 binds Stat3 with an affinity (K(D)) of 504 nM, blocks Stat3-phospho-tyrosine (pTyr) peptide interactions and Stat3 activation at 4-6.8 ¦ÌM, and selectively inhibits growth, survival, migration, and invasion of Stat3-dependent tumor cells. BP-1-102-mediated inhibition of aberrantly active Stat3 in tumor cells suppresses the expression of c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and Kr¨¹ppel-like factor 8, which is identified as a Stat3 target gene that promotes Stat3-mediated breast tumor cell migration and invasion. For the detailed information of STAT3 Inhibitor XVIII, BP-1-102, the solubility of STAT3 Inhibitor XVIII, BP-1-102 in water, the solubility of STAT3 Inhibitor XVIII, BP-1-102 in DMSO, the solubility of STAT3 Inhibitor XVIII, BP-1-102 in PBS buffer, the animal experiment (test) of STAT3 Inhibitor XVIII, BP-1-102, the cell expriment (test) of STAT3 Inhibitor XVIII, BP-1-102, the in vivo, in vitro and clinical trial test of STAT3 Inhibitor XVIII, BP-1-102, the EC50, IC50,and affinity,of STAT3 Inhibitor XVIII, BP-1-102, Please contact DC Chemicals.

Sales Link

This product is exclusively sold through our sales company Watson International Ltd and please refer to the link below for inquiries
http://watson-int.com/BP-1-102-cas-1334493-07-0/