[Bis(trifluoroacetoxy)iodo]benzene CAS 2712-78-9

Identification

CAS Number

2712-78-9

Name

[Bis(trifluoroacetoxy)iodo]benzene

Synonyms

[Bis(trifluoroacetoxy)iodo]benzene
Iodine, phenylbis[(2,2,2-trifluoroacetyl)oxy]-
Phenyl[bis(2,2,2-trifluoroacetoxy)]-λ3-iodane
phenyl{bis[(trifluoroacetyl)oxy]}-λ3-iodane
(Bis(trifluoroacetoxy)iodo)benzene
3,5-Bis(trifluoromethyl)benzonitrile
Bis(I,I-trifluoroacetoxy)iodobenzene
Bis(trifluoroacetoxy)iodobenzene
BTI
BTI; Iodobenzene I,I-bis(trifluoroacetate); PIFA
Iodine, phenylbis(trifluoroacetato-O)-
Iodobenzene I,I-bis(trifluoroacetate)
iodophenyl(2,2,2-trifluoroacetyloxy)methyl 2,2,2-trifluoroacetate
Iodosobenzene bis(trifluoroacetate)
Phenylbis(trifluoroacetato-O)iodine
PIFA

Molecular Structure

SMILES

FC(F)(F)C(=O)OI(OC(=O)C(F)(F)F)c1ccccc1

StdInChI

InChI=1S/C10H5F6IO4/c11-9(12,13)7(18)20-17(6-4-2-1-3-5-6)21-8(19)10(14,15)16/h1-5H

StdInChIKey

PEZNEXFPRSOYPL-UHFFFAOYSA-N

MDL Number

MFCD00009672

Beilstein Registry Number

764767

EINECS

220-308-0

Molecular Formula

C10H5F6IO4

Molecular Weight

430.04

Properties

Appearance

Off-white crystal

Melting Point

121-126 °C

Safety Data

Symbol

GHS07

Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Hazard Codes (Europe)

Xi

Risk Statements (Europe)

36/37/38

Safety Statements (Europe)

26-36

WGK Germany

3

Specifications and Other Information of Our [Bis(trifluoroacetoxy)iodo]benzene CAS 2712-78-9

Identification Methods

HNMR, HPLC

Assay

98% min

Loss on Drying

0.5% max

Productivity

300kg/month

Application

Reactant or reagent for:
• Pummerer-like reactions
• Chemoselective deprotection of dimethoxybenzyl ethers
• Mediating oxidative cycloisomerization
• Tosyloxylation of anilides

Used for the direct α-hydroxylation of ketones under acidic conditions. Also employed as a p-fluorination reagent of 4-alkylphenols in the presence of HF·pyridine for synthesis of 4-fluorocyclohexa-2,5-dienones.
Reagent for the oxidation of N-acylhydrazones to 1,3,4-oxadiazoles. Promotes the cyclization of styryl amines to N-alkyl or N-aryl indoles.

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[Bis(trifluoroacetoxy)iodo]benzene CAS 2712-78-9 HPLC

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