Polycarbophil CAS 9003-97-8

Identification

CAS Number

9003-97-8

Name

Polycarbophil

Synonyms

14UH1JQP6L

[UNII]
2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate

[ACD/IUPAC Name]
2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl 2-[(4-chlorophenyl)oxy]-2-methylpropanoate

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)ethyl-2-(4-chlorphenoxy)-2-methylpropanoat

[German]

[ACD/IUPAC Name]
2-(4-Chlorophénoxy)-2-méthylpropanoate de 2-(1,3-diméthyl-2,6-dioxo-1,2,3,6-tétrahydro-7H-purin-7-yl)éthyle

[French]

[ACD/IUPAC Name]
2-(4-Chlorophenoxy)-2-methylpropanoic Acid 2-(1,2,3,6-Tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl Ester

2-(p-Chlorophenoxy)-2-methylpropionic acid 2-(7-theophyllinyl)ethyl ester

2-(p-Chlorophenoxy)-2-methylpropionic Acid Ester with 7-(2-Hydroxyethyl)theophylline

259-191-6

[EINECS]
54504-70-0

[RN]
clofibrate d’étofylline

[French]

[INN]
clofibrato de etofilina

[Spanish]

[INN]
etofyllinclofibrate

etofylline clofibrate

[INN]
etofyllini clofibras

[Latin]

[INN]
Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl)ethyl ester

[ACD/Index Name]
Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, 2-(7-theophyllinyl)ethyl ester

Theofibrate

[USAN]
كلوفيبرات إيتوفيلين

[Arabic]

[INN]
益多酯

[Chinese]

[INN]

SMILES

Cn1c(=O)c2c(ncn2CCOC(=O)C(C)(C)Oc2ccc(Cl)cc2)n(C)c1=O

StdInChI

InChI=1S/C19H21ClN4O5/c1-19(2,29-13-7-5-12(20)6-8-13)17(26)28-10-9-24-11-21-15-14(24)16(25)23(4)18(27)22(15)3/h5-8,11H,9-10H2,1-4H3

StdInChIKey

KYAKGJDISSNVPZ-UHFFFAOYSA-N

Molecular Formula

C19H21ClN4O5

Molecular Weight

420.850

Properties

Appearance

White loose powder, Characteristic slight odor

Safety Data

Signal Word

WGK Germany

3

MSDS Download

Specifications and Other Information of Our Polycarbophil CAS 9003-97-8

Identification Methods

HNMR, HPLC

Absorbing Powder

≥62g/g

Heavy Metal

≤20ppm

Viscosity

2000~12000mPa·S

Loss on Drying

≤1.5%

Residue on Ignition

≤4%

Acrylic Acid

≤0.3%

Residual Solvents

≤0.45% (Ethyl acetate)

Shelf Life

2 years

Storage

Store at room temperature for long time; Sealed and keep dry.

Productivity

Known Application

Polycarbophil is a high molecular weight, crosslinked polyacrylic acid widely used as a bioadhesive polymer in pharmaceuticals and personal care products. It serves as a controlled-release agent in oral medications, a mucoadhesive excipient in vaginal and nasal formulations, and a thickening or moisturizing agent in skincare and eye care products. Its strong water absorption, prolonged mucosal adhesion, and excellent biocompatibility make it ideal for enhancing drug retention and improving user comfort.

General View of Documents

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