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5-Aminosalicylic acid CAS 89-57-6

5-Aminosalicylic acid CAS 89-57-6

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  • Identification
  • Properties
  • Safety Data
  • Specifications & Other Information
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    • Identification

    CAS Number

    89-57-6

    Name

    5-Aminosalicylic acid

    Synonyms

    201-919-1
    [EINECS]
    2090421
    [Beilstein]
    5-Amino-2-hydroxybenzoesäure
    [German]
    [ACD/IUPAC Name]
    5-Amino-2-hydroxybenzoic acid
    [ACD/IUPAC Name]
    5-AS
    5-ASA
    89-57-6
    [RN]
    Acide 5-amino-2-hydroxybenzoïque
    [French]
    [ACD/IUPAC Name]
    Asacolon
    Benzoic acid, 5-amino-2-hydroxy-
    [ACD/Index Name]
    Canasa
    [Trade name]
    Lialda
    [Trade name]
    Mesacol
    Mesalamine
    [USP]
    [USAN]
    [Trade name]
    Mesalazina
    [Spanish]
    Mesalazine
    [Wiki] link-icon
    [INN]
    [BAN]
    Mesalazinum
    [Latin]
    MFCD00007877
    [MDL number]
    Pentasa
    [Trade name]
    Rowasa
    [Trade name]
    Salofalk
    [Trade name]
    Salozinal
    ZR CQ DVQ
    [WLN]

    SMILES

    Nc1ccc(O)c(C(=O)O)c1

    StdInChI

    InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)

    StdInChIKey

    KBOPZPXVLCULAV-UHFFFAOYSA-N

    Molecular Formula

    C7H7NO3

    Molecular Weight

    153.137

    EINECS

    201-919-1

    Beilstein Registry Number

    2090421

    MDL Number

    MFCD00007877

    Properties

    Appearance

    White powder

    Melting Point

    275-280 °C

    Safety Data

    Symbol

    exclamation-mark-jpgGHS07

    Signal Word

    Warning

    Hazard statements

    H315,H317,H319,H335

    Precautionary Statements

    P261 – P264 – P271 – P280 – P302 + P352 – P305 + P351 + P338

    Personal Protective Equipment

    dust mask type N95 (US), Eyeshields, Gloves

    RIDADR 

    NONH for all modes of transport

    WGK Germany

    2

    Specifications and Other Information of Our 5-Aminosalicylic acid CAS 89-57-6

    Identification Methods

    HNMR, HPLC

    Standard

    JP, CP , USP

    Purity

    99% min

    Shelf Life

    2 years

    Storage

    Under room temperature away from light

    Productivity

    1MT/month

    Known Application

    Mesalazine is the active component of sulfasalazine (SASP), responsible for its therapeutic effects in treating ulcerative colitis and Crohn’s disease. Its mechanism involves suppressing inflammation in the intestinal mucosa by targeting critical inflammatory pathways.
    Treatment of Ulcerative Colitis: Effectively alleviates symptoms such as abdominal pain, diarrhea, and rectal bleeding.
    Maintenance of Remission: Helps prevent relapses in patients with ulcerative colitis.
    Management of Crohn’s Disease: Used for mild to moderate cases of Crohn’s disease as part of a comprehensive treatment plan.

    Regulatory Approvals

    Approved by China’s National Medical Products Administration (NMPA). Now is actively pursuing EU Certificate of Suitability (CEP) and Drug Master File (DMF) registration in Japan.

    This product is developed by our R&D company Watson International Ltd (https://www.watson-int.com/).