Nafamostat mesylate CAS 82956-11-4
Identification
CAS Number
82956-11-4
Name
Nafamostat mesylate
Synonyms
1D2T74921W
4-[(Aminoiminomethyl)amino]benzoic acid 6-(aminoiminomethyl)-2-naphthalenyl ester dimethanesulfonate
6-Carbamimidoyl-2-naphthyl 4-carbamimidamidobenzoate methanesulfonate (1:2) [ACD/IUPAC Name]
6-carbamimidoylnaphthalen-2-yl 4-carbamimidamidobenzoate methanesulfonate (1:2)
82956-11-4 [RN]
Acide méthanesulfonique – 4-carbamimidamidobenzoate de 6-carbamimidoyl-2-naphtyle (2:1) [French] [ACD/IUPAC Name]
Benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester, methanesulfonate (1:2) [ACD/Index Name]
DG2736000
Methansulfonsäure –6-carbamimidoyl-2-naphthyl-4-carbamimidamidobenzoat (2:1) [German] [ACD/IUPAC Name]
MFCD00941430 [MDL number]
Nafamostat mesylate [USAN]
(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate;methanesulfonic acid
[6-[4-[[amino(azaniumyl)methylidene]amino]benzoyl]oxynaphthalene-2-carboximidoyl]azanium and methanesulfonate
[82956-11-4]
4-[(aminoiminomethyl)amino]-6-(aminoiminomethyl)-2-naphthalenyl ester-benzoic acid, dimethanesulfonate
6-[amino(imino)methyl]-2-naphthyl 4-{[amino(imino)methyl]amino}benzoate dimethanesulfonate
6-amidino-2-naphthyl 4-(amidinoamino)benzoate, methanesulfonic acid, methanesulfonic acid
6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate
6-Amidino-2-naphthyl p-guanidinobenzoate, dimethanesulfonate
6-carbamimidoyl-2-naphthyl 4-carbamimidamidobenzoate methanesulfonate(1:2)
6-CARBAMIMIDOYLNAPHTHALEN-2-YL 4-CARBAMIMIDAMIDOBENZOATE; BIS(METHANESULFONIC ACID)
6-carbamimidoylnaphthalen-2-yl 4-guanidinobenzoate dimethanesulfonate
AMINO({[4-({[6-(AMMONIOMETHANIMIDOYL)NAPHTHALEN-2-YL]OXY}CARBONYL)PHENYL]IMINO})METHANAMINIUM DIMESYLATE
BENZOIC ACID, 4-((AMINOIMINOMETHYL)AMINO)-, 6-(AMINOIMINOMETHYL)-2-NAPHTHALENYL
Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate
benzoic acid, 4-[(aminoiminomethyl)amino], 6-(aminoiminomethyl)-2-naphthalenyl ester, methanesulfonate (1:2)
Coahibitor
Coahibitor;FUT-175;Futhan
Futhan
Futhan, FUT-175
Nafamostat (mesylate)
Nafamostat dimethanesulfonate
Nafamostat Mesilate
Nafamostat Mesylate(FUT-175)
Nafamostat Mesylate,FUT-175,Futhan
nafamostatmesylate
nafamstat mesilate
QA-7529
Ronastat [Trade name]
UNII:1D2T74921W
UNII-1D2T74921W
SMILES
CS(=O)(=O)O.CS(=O)(=O)O.c1cc(ccc1C(=O)Oc2ccc3cc(ccc3c2)C(=N)N)NC(=N)N
StdInChI
InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;21-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);21H3,(H,2,3,4)
StdInChIKey
SRXKIZXIRHMPFW-UHFFFAOYSA-N
Molecular Formula
C21H25N5O8S2
Molecular Weight
539.582
MDL Number
MFCD00941430
Properties
Appearance
White powder
Melting Point
259-261°C
Safety Data
Symbol
GHS08Signal Word
Warning
Hazard statements
H361fdPrecautionary Statements
P281Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR
NONH for all modes of transport
WGK Germany
nwg
RTECS
DG2736000
Specifications and Other Information of Our Nafamostat mesylate CAS 82956-11-4
Identification Methods
HPLC
Purity
99% min
Shelf Life
2 years
Storage
Under room temperature away from light
Known Application
Often used as a protease inhibitor. Can strongly inhibit membrane proteases, dermal release enzymes, plasmin, fibrin and the classical pathways Clr-, Cls- and other trypsin-like serinase proteases. Chemicalbook white-bound trypsin has the same inhibitory effect as free trypsin. It is used to improve acute conditions such as acute pancreatitis, acute exacerbation of chronic pancreatitis, postoperative acute pancreatitis, acute pancreatitis after pancreatography, and traumatic pancreatitis. Recent studies have shown good therapeutic effects on new coronaviruses.