Griseofulvin CAS 126-07-8

Griseofulvin CAS 126-07-8

Identification

CAS Number

126-07-8

Name

Griseofulvin

Synonyms

(+)-Griseofulvin
(1’S-trans)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
(2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione
(2S,6’R)-7-Chlor-2′,4,6-trimethoxy-6′-methyl-3H,4’H-spiro[1-benzofuran-2,1′-cyclohex[2]en]-3,4′-dion [German]
(2S,6’R)-7-Chloro-2′,4,6-trimethoxy-6′-methyl-3H,4’H-spiro[1-benzofuran-2,1′-cyclohex[2]ene]-3,4′-dione [ACD/IUPAC Name]
(2S,6’R)-7-Chloro-2′,4,6-triméthoxy-6′-méthyl-3H,4’H-spiro[1-benzofurane-2,1′-cyclohex[2]ène]-3,4′-dione [French]
126-07-8 [RN]
204-767-4 [EINECS]
875
95226 [Beilstein]
amudane
Curling factor
Fulcin [Trade name]
Fulvicin [Trade name]
Grifulvin [Trade name]
Grisactin [Trade name]
Griseofulvin [BAN] [INN] [JAN] [USAN] [Wiki]
Griseofulvin Permeability Diameter
griseofulvina [Spanish] [INN]
griseofulvine [French] [INN]
griséofulvine [French] [INN]
griseofulvinum [Latin] [INN]
Grisovin [Trade name]
Grizeofulvin [Trade name]
Lamoryl [Trade name]
Likuden [Trade name]
Likunden [Trade name]
MFCD00082343 [MDL number]
Polygris [Trade name]
Poncyl [Trade name]
Spiro[benzofuran-2(3H),1′-cyclohex[2]ene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (2S,6’R)- [ACD/Index Name]
Spirofulvin [Trade name]
Sporostatin [Trade name]
WG9800000
гризеофульвин [Russian] [INN]
غريزيوفولفين [Arabic] [INN]
灰黄霉素 [Chinese] [INN]
Fulvicin U/F
Grisovin FP
Sporostatin xan
Xuanjing
(+)-griseofulvin; Amudane; Griseofulvin, microcrystalline; Griseofulvin, ultramicrosize; Griseofulvina; Griseofulvine; Griseofulvinum
(+)-griseofulvin; Amudane; Griseofulvina; Griseofulvine; Griseofulvinum
(1’S,6’R)-7-chloro-2′,4,6-trimethoxy-6′-methyl-3H-spiro[benzofuran-2,1′-cyclohex[2]ene]-3,4′-dione
(1’S,6’R)-7-Chloro-2′,4,6-trimethoxy-6′-methyl-spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
(1’S-trans)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2(3H),1′-(2)cyclohexene)-3,4′-dione
(2S)-trans-7-Chloro-2?,4,6-trimethoxy-6?-methylspiro(benzofuran-2[3H,1?-[2]cyclohexene)-3,4?-dione
(2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione
(2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione
(2S,5’R)-7-chloro-3′,4,6-trimethoxy-5′-methylspiro[1-benzofuran-2,4′-cyclohex-2-ene]-1′,3-dione
(2S,5’R)-7-chloro-3′,4,6-trimethoxy-5′-methyl-spiro[1-benzofuran-2,4′-cyclohex-2-ene]-1′,3-dione
(2S,5’R)-7-chloro-3′,4,6-trimethoxy-5′-methylspiro[1-benzofuran-2,4′-cyclohexane]-1′,3-dione
(2S,5’R)-7-chloro-3′,4,6-trimethoxy-5′-methylspiro[benzofuran-2,4′-cyclohex-2-ene]-1′,3-dione
(2S,5’R)-7-chloro-3′,4,6-trimethoxy-5′-methyl-spiro[benzofuran-2,4′-cyclohex-2-ene]-1′,3-dione
(2S,5’R)-7-chloro-3′,4,6-trimethoxy-5′-methyl-spiro[benzofuran-2,4′-cyclohex-2-ene]-1′,3-quinone
(2S,6’R)-7-Ch
(2S,6’R)-7-chloro-2′,4,6-trimethoxy-6′-methyl-3H-spiro[1-benzofuran-2,1′-cyclohexan]-2′-ene-3,4′-dione
(2S,6’R)-7-chloro-2′,4,6-trimethoxy-6′-methyl-3H-spiro[benzofuran-2,1′-cyclohexan]-2′-ene-3,4′-dione
(2S-trans)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2(3H),1′-(2)cyclohexene)-3,4′-dione
[126-07-8]
2884-22-2 [RN]
5-18-05-00150 [Beilstein]
5-18-05-00150 (Beilstein Handbook Reference) [Beilstein]
78739-00-1 [RN]
7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′,- [2]cyclohexene]-3,4′-dione
7-chloro-2′,4,6-trimethoxy-6’R-methyl-spiro[benzofuran-2(3H)-1’S-[2]cyclohexene]-3,4′-dione
7-Chloro-2′,4,6-trimethoxy-6’β-methylspiro(benzofuran-2(3H),1′-(2)cyclohexene)-3,4′-dione
7-chloro-3′,4,6-trimethoxy-5′-methylspiro[benzofuran-2,4′-cyclohexane]-1′,3-dione
7-chloro-4,6,2′-trimethoxy-6′-methylgris-2′-en-3,4′-dione
7-Chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1′-(2′-methoxy-6′-methylcyclohex-2′-en-4′-one)
ACon0_000953
ACon1_001843
Amudane;Grifulvin V;Gris-PEG
BB_NC-0702
biogrisin-fp
BPBio1_000299
BSPBio_000271
BSPBio_001621
C17H17ClO6
Crivicin
Crivicin (Trade name)
Crivicin; Fulcin; Fulvicin; Grifulvin; Grifulvin V; Grisactin; Grison-250; Grisovin; Lamoryl; Likuden; Poncyl; S-Fulvin; Spirofulvin; Sporostatin
delmofulvina
EINECS 204-767-4
Fulcine
fulvican grisactin
FULVICIN P/G
fulvicin UF
FULVICIN-U/F
fulvina
Fulvinil
fulvistatin
fungivin
greosin
gresfeed
gricin
Grifulin
Grifulvin V (Trade name)
griscofulvin
grisefuline
griseo
Griseofulvin, EP grade
Griseofulvin, ultramicrosize
griseofulvin;fulcin
Griseofulvin|Amudane
Griseofulvina
Griseofulvine
griseofulvin-forte
Griseomix
Grisetin
Grisofulvin
Grison-250
Grison-250 (Trade name)
Grivate
Grysio
guservin
IDI1_000154
Idifulvin
LMPK02000019
MEGxm0_000184
murfulvin
NCGC00091120-02
NCGC00091120-03
neo-fulcin
Norofulvin
Pharmakon1600-00200046
Prestwick3_000226
QA-6115
S-Fulvin
S-Fulvin (Trade name)
SPECTRUM200046
Spectrum5_000648
Spiro(benzofuran-2(3H),1′-(2)cyclohexene)-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1’S-trans)-
Spiro(benzofuran-2(3H),1′-(2)cyclohexene)-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (2S-trans)-
ULTRAGRIS-165
ULTRAGRIS-330

SMILES

C[[email protected]@H]1CC(=O)C=C([[email protected]]12C(=O)c3c(cc(c(c3O2)Cl)OC)OC)OC

StdInChI

InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

StdInChIKey

DDUHZTYCFQRHIY-RBHXEPJQSA-N

Molecular Formula

C17H17ClO6

Molecular Weight

352.766

EINECS

204-767-4

Beilstein Registry Number

95226

MDL Number

MFCD00082343

Properties

Appearance

A white or yellowish-white, microfine powder.

Melting Point

217℃~224℃

Safety Data

Symbol

exclamation-mark-jpgexclamation-mark-jpgGHS07, GHS08

Signal Word

Danger

Hazard statements

H317-H351-H360

Precautionary Statements

P201-P280-P308 + P313

Personal Protective Equipment

Eyeshields, Faceshields, Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

RIDADR 

NONH for all modes of transport

WGK Germany

3

RTECS 

WG9800000

Specifications and Other Information of Our Griseofulvin CAS 126-07-8

Identification Methods

HPLC;GC

Identification

The infrared absorbance spectrum is concordant with the reference spectrum;A wine-red color is produced

Solubility

Practically insoluble in water, freely soluble in dimethylformamide and in tetrachloroethane, slightly soluble in anhydrous ethanol and in methanol

Particle Size

The particles of which are generally up to 5um in max. dimension; Larger particles which may occasionally exceed 30um

Appearance Of Solution

The solution is clear and not more intensely coloured than reference solution Y4.

Acidity

Not more than 1.0ml of 0.02M sodium hydroxide is required

Assay (Dried Substance)

97%~102%

Specific Optical Rotation

+352°~+364°

Related Substances (GC)

-Cl: <0.60; -H: <0.15

Heavy Metals

≤20ppm

Substance Soluble In Light Petroleum

≤0.2%

Loss on Drying

≤1.0%

Sulfated Ash

≤0.2%

Residual Solvents

Ethanol: ≤0.5%

Acetone: ≤0.5%

Dichloromethane: ≤0.06%

Abnormal Toxicity

Five mice orals, none of the mice dies Within 48h

Shelf Life

4 years

Storage

Under room temperature away from light

Known Application

Used for tinea capitis, onychomycosis, tinea capitis, tinea pedis and tinea capitis caused by sensitive fungi.

Watson International Ltd

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details. http://www.watson-int.com/griseofulvin-cas-126-07-8/