Ferric Carboxymaltose CAS 9007-72-1

Ferric Carboxymaltose CAS 9007-72-1

Identification

CAS Number

9007-72-1

Name

Ferric Carboxymaltose

Synonyms

Ferinject
ferric carboxymaltose
injectafer
iron carboxymaltose
iron dextri-maltose
polynuclear iron (III)-hydroxide 4(R)-(poly-(1->4)-o-alpha-D-glucopyranosyl)-oxy-2(R),3(S),5(R), 6-tetrahydroxy-hexanoate

SMILES

C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC(C(CO)O)C(C(C(=O)[O-])O)O)CO)CO)O)O)O)O.O.[OH-].[O-2].[Fe+3]

StdInChI

InChI=1S/C24H42O22.Fe.2H2O.O/c25-1-5(29)18(11(32)14(35)21(39)40)44-23-16(37)12(33)20(7(3-27)42-23)46-24-17(38)13(34)19(8(4-28)43-24)45-22-15(36)10(31)9(30)6(2-26)41-22;;;;/h5-20,22-38H,1-4H2,(H,39,40);;2*1H2;/q;+3;;;-2/p- 2/t5-,6-,7-,8-,9-,10+,11+,12-,13-,14+,15-,16-,17-,18+,19-,20-,22-,23-,24-;;;;/m1…./s1

StdInChIKey

MFBBZTDYOYZJGB-HAONTEFVSA-L

Molecular Formula

C39H63FeO39

Molecular Weight

1211.73912

Properties

Appearance

Brown powder

Safety Data

RIDADR 

NONH for all modes of transport

WGK Germany

3

Specifications and Other Information of Our Ferric Carboxymaltose CAS 9007-72-1

Identification Methods

Iron salt: The reaction should be positive.

Dextrin: The location, color and size of the major spots on the TLC of the test sample should be similar to that of reference substance a.

pH

5.0~7.0

The number-average molecular weight(MN)

≥90kDa

The weight-average molecular weight(MW)

130 kDa -230 kDa

The polydisoersity index (Mw/Mn)

≤1.5%

Sodium chloride content

≤6.0%

Assay

Iron content(calculated on dried basis)

24.0%~33.0%

Dextrin content (calculated on dried basis)

25.0%~50.0%

Stoichiometric ratios of iron to carbohydrate should be

0.5~0.8

Loss on drying

≤10.0%

Microbial limit

Total Aerobic Microbial Count (TAMC)

≤100 cfu/g

Total Yeasts and Molds Count TYMC)

≤10 cfu/g

Bacterial endotoxins

<0.2EU/mg Fe

Residue solvents

Ethanol ≤0.5%

Elemental impurities

Pb

≤1.2ppm

Cd

≤0.48ppm

As

≤3.6ppm

Ni

≤4.8ppm

Co

≤1.2ppm

V

≤2.4ppm

Shelf Life

2 years

Storage

Stored below 30℃ in a tight container.

Known Application

Often used as an iron supplement.

This product is developed by our R&D company Watson International Ltd (https://www.watson-int.com/).