Dapagliflozin CAS 461432-26-8

Dapagliflozin CAS 461432-26-8

Identification

CAS Number

461432-26-8

Name

Dapagliflozin

Synonyms

(1S)-1,5-Anhydro-1-[4-chlor-3-(4-ethoxybenzyl)phenyl]-D-glucitol [German] [ACD/IUPAC Name]
(1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol [ACD/IUPAC Name]
(1S)-1,5-Anhydro-1-[4-chloro-3-(4-éthoxybenzyl)phényl]-D-glucitol [French] [ACD/IUPAC Name]
(2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol
1ULL0QJ8UC
461432-26-8 [RN]
Dapagliflozin [INN] [USAN] [Wiki]
dapagliflozina [Spanish] [INN]
dapagliflozine [French] [INN]
dapagliflozinum [Latin] [INN]
D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)- [ACD/Index Name]
Farxiga [Trade name]
Forxiga [Trade name]
(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
(1S)-1,5-anhydro-1-c-4-chloro-3-(4-ethoxyphenyl)methylphenyl-d-glucitol
(2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-(3-(4-Ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyl-tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-methylol-tetrahydropyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-4-chloro-3-(4-ethoxybenzyl)phenyl-6-(hyd roxymethyl)-tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4R,5S,6R)-2-4-chloro-3-(4-ethoxybenzyl)phenyl-6-(hydroxymethyl)tetrahy
(2S,4R,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-3,4,5-triol
[461432-26-8] [RN]
1204219-80-6 [RN]
BMS 512148
BMS 512148; BMS-512148
BMS512148
BMS-512148;BMS512148;BMS 512148
BMS-512148|Farxiga®|Forxiga®
dapagliflozin ????????????
dapagliflozin d5
dapagliflozin 达格列净 [Chinese]
Dapagliflozin;BMS 512148
Dapagliflozin|BMS 512148
dapagliflozin-d5
Farxiga®
Forxiga®
https://www.ebi.ac.uk/chembl/compoundreportcard/CHEMBL429910/
MFCD13182359 [MDL number]
UNII:1ULL0QJ8UC
UNII-1ULL0QJ8UC

SMILES

CCOc1ccc(cc1)Cc2cc(ccc2Cl)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

StdInChI

InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1

StdInChIKey

JVHXJTBJCFBINQ-ADAARDCZSA-N

Molecular Formula

C21H25ClO6

Molecular Weight

408.873

EINECS

639-683-0

MDL Number

MFCD13182359

Properties

Appearance

white to grayish white powder

Structure

461432-26-8

Structure of Dapagliflozin CAS 461432-26-8

Safety Data

Symbol

exclamation-mark-jpgexclamation-mark-jpgexclamation-mark-jpgGHS07, GHS08, GHS09

Signal Word

Warning

Hazard statements

H302 – H319 – H372 – H411

Precautionary Statements

P260 – P264 – P273 – P301 + P312 – P305 + P351 + P338 – P314

WGK Germany

3

MSDS Download

Specifications and Other Information of Our

Identification Methods

Heavy Metals

NMT 10ppm

Water

NMT 2%

Residue on Ignition

NMT 0.5%

Shelf Life

2 years

Storage

Known Application

Dapagliflozin is a sodium-glucose co-transporter 2 inhibitor (SGLT2i) and a new type of oral hypoglycemic drug. It can inhibit SGLT2 activity, inhibit proximal renal tubular sodium-glucose reabsorption, promote urinary glucose excretion, and thereby reduce blood glucose concentration.

General View of Documents

This product is sold exclusively through our sales company Watson International Limited, and please click the link below for details (https://www.watson-int.com/).