Ceftiofur CAS 80370-57-6

Ceftiofur CAS 80370-57-6

Identification

CAS Number

80370-57-6

Name

Ceftiofur

Synonyms

(6R,7R)-7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 72-(Z)-(O-Methyloxime)2-Furoate (Ester)
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(2-furoylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carbonsäure [German] [ACD/IUPAC Name]
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(2-furoylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid [ACD/IUPAC Name]
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
[6R-[6a,7b(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-, (6R,7R)- [ACD/Index Name]
80370-57-6 [RN]
83JL932I1C
Acide (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(méthoxyimino)acétyl]amino}-3-[(2-furoylsulfanyl)méthyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ène-2-carboxylique [French] [ACD/IUPAC Name]
Ceftiofur [Wiki]
Ceftiofurum [Latin]
CM 31-916
Excenel
naxcel
(6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((furan-2-carbonyl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-methyloxime), 2-furoate (ester)
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-3-(furan-2-ylcarbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(2-furyl-oxomethyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[[2-furanyl(oxo)methyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R,7R)-7-[[(2Z)-2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(furan-2-carbonylthio)methyl]-8-keto-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, (6R-(6α,7β(Z)))-
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((2-furanylcarbonyl)thio)methyl)-8-oxo-, (6R,7R)-
Ceftiofur [USAN] [USAN]
Ceftiofur crystalline free acid
CEFTIOFUR CRYSTALLINE FREE ACID [CCFA](NOTE: SEE ALSO CAS NO. 104010-37-9 & 103980-44-5)
Ceftiofurum [Latin]
MFCD00864953 [MDL number]
U 64279A
U 67279A
UNII:83JL932I1C
UNII-83JL932I1C

SMILES

CO/N=C(/c1csc(n1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)CSC(=O)c4ccco4)C(=O)O

StdInChI

InChI=1S/C19H17N5O7S3/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28)/b23-11-/t12-,16-/m1/s1

StdInChIKey

ZBHXIWJRIFEVQY-IHMPYVIRSA-N

Molecular Formula

C19H17N5O7S3

Molecular Weight

523.563

EINECS

1308068-626-2

MDL Number

MFCD00864953

Properties

Appearance

Off-white or light yellowish powder

Safety Data

Symbol

exclamation-mark-jpgGHS08

Signal Word

Warning

Hazard statements

H317 – H334

Precautionary Statements

P261 – P272 – P280 – P284 – P302 + P352 – P333 + P313

WGK Germany

3

MSDS Download

Specifications and Other Information of Our

Assay

93% min

Relative substance

3%max

Remaining solvent

0.5%max

Water

3%max

Residue on ignition

0.5%max

Heavy metal

20%max

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

Ceftiofur a third-generation cephalosporin antibiotic designed for veterinary use. It has a broad spectrum of antibacterial activity, showing strong efficacy against Gram-positive and Gram-negative bacteria, as well as anaerobic bacteria. Its activity against Gram-positive bacteria is similar to or weaker than that of first-generation cephalosporins. However, it exhibits potent antibacterial activity against Gram-negative bacteria such as Escherichia coli, Salmonella typhi, Klebsiella pneumoniae, Enterobacter cloacae, and Streptococcus.

It is suitable for various infections caused by susceptible bacteria in the respiratory and urinary tracts, as well as other conditions. Particularly effective in preventing and treating early mortality in chicks caused by infections such as Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, and Staphylococcus aureus. It is also used to treat Escherichia coli diarrhea in 1-day-old piglets, as well as wound infections resulting from procedures like umbilical cord cutting, ear notching, tail docking, and teeth clipping in piglets. Additionally, it is used for infections such as Actinobacillus pleuropneumonia in pigs and bronchopneumonia in cattle caused by Haemophilus somnus.

General View of Documents

This product is sold exclusively through our sales company Watson International Limited, and please click the link below for details (https://www.watson-int.com/).